Like most medicines, Dovato can cause mild to severe side effects. The lists below describe some of the more common side effects that Dovato can cause. These lists do not include all possible side effects.
Keep in mind that the side effects of a medicine can depend on:
- your age
- other health problems you have
- other medicines you are taking
Your doctor or pharmacist can tell you more about the potential side effects of Dovato. They can also suggest ways to help reduce side effects.
Mild side effects
Here is a short list of some of the mild side effects that Dovato can cause. For more information about other mild side effects, talk to your doctor or pharmacist, or read the Dovato package leaflet. prescribing information.
Mild Dovato side effects that have been reported include:
Mild side effects of many medications can disappear within days to weeks. But if they become bothersome, talk to your doctor or pharmacist.
Serious side effects
Serious side effects from Dovato can occur, but they are not common. If you have serious side effects from Dovato, call your doctor right away. But, if you think you have a medical emergency, you should call 911 or your local emergency number.
Serious side effects of Dovato that have been reported include:
*For more information on this side effect, see the “Side Effects Focus” section below.
If you think someone is at immediate risk of harming themselves or another person:
- Dial 911 or your local emergency number.
- Stay with the person until help arrives.
- Remove any guns, knives, drugs, or other objects that could cause damage.
- Listen, but don’t judge, argue, threaten or yell.
If you or someone you know is considering suicide, get help from a crisis or suicide prevention hotline. Try the National Suicide Prevention Lifeline at 800-273-8255.
Focus on side effects
Learn more about some of the side effects Dovato can cause.
Risk of lamivudine-resistant HBV. It is possible to have both HIV and chronic (long-term) hepatitis B, which is an infection with the hepatitis B virus (HBV). If people with both conditions use drugs containing lamivudine, their HBV may become resistant to lamivudine. (Lamivudine is one of the medicines in Dovato.) This can make hepatitis B harder to treat.
Risk of worsening hepatitis B. In people with HIV and hepatitis B, stopping treatment with medicines containing lamivudine, such as Dovato, may make hepatitis B worse.
What might help
Before prescribing Dovato, your doctor should test you for hepatitis B. If you have hepatitis B and your doctor decides to prescribe you Dovato, they may recommend additional treatment for hepatitis B. They may also suggest that you try another treatment for your HIV instead of Dovato.
If you have both HIV and hepatitis B and need to stop taking Dovato, your doctor will monitor your liver function for a few months. They may also prescribe treatment for your hepatitis B during this time.
Treatment with Dovato can cause liver problems. These problems can be mild, such as mildly elevated liver enzyme levels. But in rare cases, Dovato can cause serious liver problems, including liver failure.
Symptoms of liver problems can include:
You may have a higher risk of liver problems if you take Dovato and you have hepatitis B or hepatitis C.
What might help
While you are taking Dovato, your doctor may order blood tests from time to time to check your liver enzyme levels. Higher than usual levels can be an early sign of liver problems, including liver damage.
If you think you have symptoms of liver problems, contact your doctor immediately. They will probably want to examine your symptoms in person.
If your doctor confirms that you have liver problems, they will probably tell you to stop taking Dovato.
Immune system changes
Treatment with Dovato may lead to changes in the immune system.
In rare cases, antiretroviral medicines such as Dovato can cause a condition called immune reconstitution syndrome. (Antiretroviral medicines are medicines used to treat HIV.) This reaction may happen when you start taking Dovato.
HIV weakens your immune system. When you start taking Dovato, your immune system will probably get stronger again. He can react to infections he couldn’t fight off before. This can cause symptoms such as swollen lymph nodes, difficulty breathing, and fever.
There are also rare cases of people developing autoimmune diseases, such as Graves’ disease, due to immune reconstitution syndrome. (With an autoimmune disease, your immune system mistakenly attacks parts of your body.) This can happen even after taking medicines such as Dovato for several months.
What might help
If you develop symptoms of immune system changes while taking Dovato, tell your doctor. They will probably want to examine your symptoms in person. They can also suggest treatment for your symptoms and any infection that may be present.
Unless your symptoms are life-threatening, you probably won’t need to stop taking Dovato if your immune system changes. This side effect is treatable in most cases.
Some people may have an allergic reaction to Dovato. But these reactions were rare in studies drug.
Symptoms of a mild allergic reaction may include:
A more serious allergic reaction is rare but possible. Symptoms of a severe allergic reaction can include swelling under the skin, usually on the eyelids, lips, hands or feet. They can also include swelling of the tongue, mouth, or throat, which can lead to difficulty breathing.
Call your doctor right away if you have an allergic reaction to Dovato. But if you think you have a medical emergency, call 911 or your local emergency number.