May 11, 2022

Side effects, cost, dosage, how to take, and more

Like most medicines, Ibrance can cause mild or serious side effects. The lists below describe some of the most common. These lists do not include all possible side effects.

Ibrance is taken with certain other medicines. The side effects of Ibrance may vary depending on the medicine you take it with.

Keep in mind that the side effects of a drug may depend on:

  • your age
  • other health problems you have
  • other medicines you are taking

Your doctor or pharmacist can tell you more about the potential side effects of Ibrance. They may also suggest ways to help manage the side effects of Ibrance.

Mild side effects

Here is a list of some of the mild side effects that Ibrance can cause. To find out more about other mild side effects, talk to your doctor or pharmacist, or read the prescribing information for Ibrance. tablets and capsules.

Mild side effects of Ibrance that have been reported include:

The mild side effects of many medications can go away within days to weeks. But if they become bothersome, talk to your doctor or pharmacist. They may suggest ways to prevent or manage certain side effects.

* For more information on this side effect, see the “Side effects overview” section below.

Serious side effects

Serious side effects of Ibrance can occur. If you experience any serious side effects from this medication, call your doctor immediately. If you think you have a medical emergency, you should call 911 or your local emergency number.

Serious side effects of Ibrance that have been reported include:

* For more information on this side effect, see the “Side effects overview” section below.

Focus on side effects

Learn more about some of the side effects that Ibrance can cause.

Hair loss

Hair loss is one of the most common side effects of Ibrance. Although this side effect is common, it is usually mild.

Hair loss has been reported to be mild in studies of Ibrance tablets and capsules. The medicine is likely to thin the hair on your head, but not completely fall out.

What could help

It may not be possible to prevent thinning or falling out of Ibrance’s hair. You may want to consider trying over-the-counter scalp treatments that contain minoxidil, such as Rogaine. And wearing a wig or other headwear can help you feel more comfortable.

If you have any questions or concerns about hair loss while taking Ibrance, talk to your doctor.


Taking Ibrance usually causes certain blood problems (changes in your blood cell levels as seen in blood tests).

The most common side effect reported in studies with Ibrance tablets and capsules was neutropenia. These are low levels of a type of white blood cell called neutrophils.

Neutrophils work in your immune system to detect and destroy germs that can cause infections, such as bacteria. Without enough neutrophils, you are more likely to develop mild or serious infections. Some examples include the common cold, urinary tract infections (UTIs), and the flu.

Symptoms of infections can vary, but can include:

  • fever*
  • chills
  • aches
  • cough
  • stuffy or runny nose

What could help

Since neutropenia is common with Ibrance, it is important to take precautions to protect yourself from infections while taking the medicine. Some tips include washing your hands often and avoiding contact with people who may be sick.

To monitor neutropenia and other blood disorders, your doctor will arrange blood tests. You will have a blood test called a full blood count (FSC):

  • before you start taking Ibrance
  • at the start of each 28-day treatment cycle
  • on day 15 of your first 2 treatment cycles
  • whenever your doctor recommends it during your treatment

If severe neutropenia occurs, your doctor may ask you to stop Ibrance and resume at a lower dose, or ask you to stop the medicine. They may also recommend a treatment such as pegfilgrastim (Neulasta) to increase your white blood cell count. However, you should not change your dose of Ibrance without your doctor’s approval.

In rare cases, treatment with Ibrance may cause febrile neutropenia (neutropenia with fever). In Ibrance’s studies tablets and capsules, febrile neutropenia resulted in death. If you develop a fever while taking Ibrance, tell your doctor immediately.


You may develop a rash while you are taking Ibrance. This is one of the most common side effects seen in people taking Ibrance. tablets and capsules studying.

Symptoms of an Ibrance rash can include:

  • itching
  • redness or swelling
  • blisters
  • skin bumps that look like acne

What could help

If you get a rash while taking Ibrance, it is best to tell your doctor. They can help determine if you might be having an allergic reaction.

In most cases, a rash is a mild side effect of Ibrance and not an allergic reaction. But because allergic reactions can get severe quickly, it’s important to tell your doctor about a rash or other skin symptoms right away.

In many cases, rash symptoms can be managed with over-the-counter remedies. For example, your doctor or pharmacist may recommend that you apply hydrocortisone cream to relieve symptoms.

Allergic reaction

Some people may have an allergic reaction to Ibrance. It is not known how many people had allergic reactions in the Ibrance studies. tablets Where capsules.

Symptoms of a mild allergic reaction can include:

A more serious allergic reaction is rare but possible. Symptoms of a severe allergic reaction may include swelling under the skin, usually in the eyelids, lips, hands, or feet. They can also include swelling of the tongue, mouth, or throat, which can cause difficulty in breathing.

Call your doctor immediately if you have an allergic reaction to Ibrance. But if you think you have a medical emergency, call 911 or your local emergency number.

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