June 23, 2022

Side effects, cost, uses, dosage and more

When considering treatment with Kesimpta, it is important to discuss with your doctor:

  • your overall health
  • any medical conditions you have
  • other medicines you are taking

Below are some things to consider before taking Kesimpta.

Interactions

Taking medicines, vaccines, food, and other things with a certain medicine can affect how it works. These effects are called interactions.

Before taking Kesimpta, be sure to tell your doctor about all medicines you are taking, including prescription and over-the-counter medicines. Also describe the vitamins, herbs or supplements you are using. Your doctor or pharmacist can tell you about interactions these products can have with Kesimpta.

Interactions with drugs or supplements

Kesimpta may interact with drugs that weaken your immune system, such as corticosteroids. Prednisone (Rayos) is an example of a corticosteroid.

There are other medicines which can interact with Kesimpta. Your doctor or pharmacist can tell you more about these interactions and any other interactions that may occur with the use of Kesimpta.

Other interactions

You should avoid getting vaccinated while you are using Kesimpta. This includes both live (active) and non-live (inactive) vaccines.

Live vaccines

Live vaccines contain a weakened form of the bacteria or virus whose vaccine helps prevent infection.

Live vaccines usually do not cause infection in a person with a healthy immune system. But in a person with a weakened immune system, including a person using Kesimpta, a live vaccine could cause infection.

Here are some examples of live vaccines:

Before starting treatment with Kesimpta, ask your doctor if you are up to date with all the recommended vaccines.

They will probably recommend that you not receive a live vaccine for at least 4 weeks before you start using Kesimpta. They will also suggest that you avoid live vaccines while using the medicine and for some time after your last dose.

Talk to your doctor about when it is safe to receive live vaccines after stopping treatment with Kesimpta.

Non-living vaccines

Non-living vaccines do not contain live bacteria or viruses. However, Kesimpta may make non-live vaccines less effective for you.

Examples of non-live vaccines are:

Before starting treatment with Kesimpta, ask your doctor if you are up to date with all the recommended vaccines.

In most cases, your doctor will suggest that you avoid non-live vaccines for at least 2 weeks before you start using Kesimpta. They will also probably suggest that you avoid non-live vaccines while taking this medicine and for some time after your last dose.

Talk to your doctor about when it is safe to receive nonliving vaccines after stopping treatment with Kesimpta.

Warnings

Kesimpta may not be suitable for you if you have certain medical conditions or other factors that affect your health. Talk to your doctor about your medical history before taking Kesimpta. Factors to consider include those from the list below.

  • Active infection. Before you start treatment with Kesimpta, tell your doctor about any infections you have. Your body may not be able to fight off infections as well after you start taking the medicine. Your doctor will want to make sure that any active infections are treated before taking Kesimpta.
  • Hepatitis B virus (HBV). You should not use Kesimpta if you have active HBV. (“Active” means you have a detectable amount of the virus in your body.) Before you start using Kesimpta, your doctor will order an HBV test. If you have HBV in your system, your doctor will likely treat the infection before you start using the medicine.
  • Recent vaccination. Before starting treatment with Kesimpta, tell your doctor if you have recently received any vaccines. They may make you wait to start using Kesimpta for up to several weeks after receiving your vaccine. For more details on using Kesimpta with vaccines, see the “Interactions” section just above.
  • Allergic reaction. If you have had an allergic reaction to Kesimpta or any of its ingredients, you should not take Kesimpta. Ask your doctor what other medications are better options for you.

Kesimpta and alcohol

There are no known issues with alcohol consumption while using Kesimpta. But before you start treatment, discuss with your doctor how much alcohol it is safe to drink while using this medicine.

Pregnancy and breastfeeding

It can be dangerous to use Kesimpta during pregnancy.

To help prevent pregnancy, women * should use an effective form of birth control while taking Kesimpta. And they should continue to use birth control for at least 6 months after their last dose.

The manufacturer of Kesimpta has not provided birth control recommendations for men * who use the drug. If you are a man taking Kesimpta, discuss your birth control options with your doctor.

It is not known whether Kesimpta can be used safely while breast-feeding. Talk with your doctor about the risks and benefits of using Kesimpta during this time.

* In this article, we use the terms “male” and “female” to refer to the sex assigned to a person at birth. For more information on the difference between sex and gender, check out this article.


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