May 11, 2022

Side Effects, Cost, Uses & More

Like most medicines, Afinitor can cause mild to severe side effects. The lists below describe some of the more common side effects that Afinitor can cause. These lists do not include all possible side effects.

Keep in mind that the side effects of a medicine can depend on:

  • your age
  • other health problems you have
  • other medicines you are taking

Your doctor or pharmacist can tell you more about the potential side effects of Afinitor. They can also suggest ways to help reduce side effects.

Mild side effects

Here is a short list of some of the mild side effects that Afinitor can cause. For more information about other mild side effects, talk to your doctor or pharmacist, or read the Afinitor package leaflet prescribing information.

Mild side effects of Afinitor that have been reported include:

Mild side effects of many medications can disappear within days to weeks. But if they become bothersome, talk to your doctor or pharmacist.

Serious side effects

Serious side effects from Afinitor can occur, but they are not common. If you have serious side effects from Afinitor, call your doctor right away. But if you think you have a medical emergency, immediately call 911 or your local emergency number.

Serious side effects of Afinitor that have been reported include:

*For more information on this side effect, see the “Side Effects Focus” section below.

Focus on side effects

Learn more about some of the side effects Afinitor can cause.

Eruption

Some people may get a rash while taking Afinitor. Rash was one of the most common side effects reported by people taking this drug in studies. If you develop a rash, you may have symptoms such as:

  • itch
  • bumps or hives
  • redness or discoloration

What might help

If you develop a rash during treatment with Afinitor, tell your doctor. In some cases, a rash can also be a sign of an allergic reaction. Your doctor may want to see your rash to help determine its cause.

In some cases, your doctor may recommend a cream, ointment, or medication such as diphenhydramine (Benadryl) to treat your rash symptoms.

Mouth sores

Mouth ulcers may occur during the treatment with Afinitor. Symptoms may include:

  • pain
  • swelling
  • redness or discoloration

In studies, mouth sores were a common side effect reported by people taking Afinitor. Although most mouth sores are mild, it is possible to develop more serious mouth sores.

What might help

To reduce your risk of mouth sores from Afinitor, your doctor will likely recommend that you use an alcohol-free mouthwash that contains dexamethasone. If you develop mouth sores while using this mouthwash, they are likely to be less severe.

If you notice that you are developing mouth sores, talk to your doctor. They will likely recommend that you use a different mouthwash or treatment for your mouth sores.

If you develop mouth sores, try to avoid alcohol, hydrogen peroxide, iodine, thyme, or any products containing these ingredients. They can make your mouth sores worse.

In some cases, your doctor may recommend that you stop taking Afinitor until your mouth sores heal. If your sores are severe, they may recommend restarting Afinitor at a lower dose after your mouth has healed. Or they may recommend that you stop taking Afinitor permanently.

Talk to your doctor about the best way to help prevent and treat mouth sores that can occur while taking Afinitor.

Pneumonia

Afinitor may cause pneumonitis (swelling of the lungs) in some people. In studies, this was a common side effect in people taking Afinitor. In rare cases, pneumonitis can be serious or even fatal.

Afinitor can cause a specific type of pneumonitis that is not related to infection. This means that the swelling is not caused by a virus or bacteria and is not contagious.

Symptoms of this type of pneumonitis can include:

What might help

It is important to contact your doctor immediately if you develop symptoms of pneumonitis. Your doctor may recommend that you have a chest X-ray to see if you have pneumonitis.

Your doctor may want to monitor your condition to make sure it doesn’t get worse. They may also prescribe a corticosteroid (a type of steroid) such as prednisone (Rayos) to decrease swelling.

If your pneumonitis is severe, your doctor may ask you to temporarily or permanently stop taking Afinitor and switch to another treatment.

Allergic reaction

Some people may have an allergic reaction to Afinitor.

Symptoms of a mild allergic reaction may include:

  • itchy skin
  • itching
  • rinsing (temporary warmth, redness or deepening of skin color)

A more serious allergic reaction is rare but possible. Symptoms of a severe allergic reaction can include swelling under the skin, usually on the eyelids, lips, hands or feet. They can also include swelling of the tongue, mouth, or throat, which can lead to difficulty breathing.

Call your doctor right away if you have an allergic reaction to Afinitor. But if you think you have a medical emergency, call 911 or your local emergency number.


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