August 13, 2022

Side effects, dosage, uses, etc.

Topical calcipotriene can cause mild or severe side effects. The following lists contain some of the main side effects that can occur when taking calcipotriene topically. These lists do not include all possible side effects.

For more information on the possible side effects of topical calcipotriene, talk to your doctor or pharmacist. They can give you advice on how to deal with side effects that may be worrying or bothersome.

To note: The Food and Drug Administration (FDA) tracks the side effects of drugs it has approved. If you would like to notify the FDA of a side effect you have had with topical calcipotriene, you can do so via MedWatch.

Mild side effects

Mild side effects * of topical calcipotriene may include:

Most of these side effects can go away within days or weeks. But if they get worse or don’t go away, talk to your doctor or pharmacist.

* This is a partial list of mild side effects of topical calcipotriene. To learn more about other mild side effects, talk to your doctor or pharmacist, or see the prescribing information for calcipotriene. cream, ointment, and Solution.
** For more information about this side effect, see “Side effect details” below.

Serious side effects

Serious side effects of topical calcipotriene are not common, but they can occur. Call your doctor immediately if you experience serious side effects. Call 911 or your local emergency number if your symptoms are life-threatening or if you think you have a medical emergency.

Serious side effects and their symptoms can include:

* For more information about this side effect, see “Side effect details” below.

Details of side effects

Here are some details about some side effects that this medicine can cause.

Skin irritation

Skin irritation is a common side effect of topical use of calcipotriene. This usually happens at the sites where you apply the medicine.

To find out how often skin irritation has occurred in clinical studies, see the prescribing information for calcipotriene. cream, ointment, and Solution.

Studies of the drug have not specified symptoms of skin irritation in people who have reported this side effect. But side effects that can irritate your skin can include:

  • red or discolored skin
  • itchy skin
  • peeling skin
  • skin atrophy (thinning of your skin)

If you think topical use of calcipotriene irritates your skin, tell your doctor immediately. They will probably want to see you and examine your skin. If they think calcipotriene is the cause of your irritation, they will probably ask you to stop using the medicine and switch to other treatment.

Itch

You may feel itchy while using topical calcipotriene. This was a common side effect reported by people using the drug in clinical studies.

To find out how often itching has occurred in studies, see the prescribing information for calcipotriene. cream, ointment, and Solution.

If you experience itching while taking calcipotriene, talk to your doctor or pharmacist. They may be able to recommend ways to treat this side effect. Or they may recommend stopping your calcipotriene treatment and switching to another medicine.

Worsening of psoriasis

Although topical calcipotriene is used to treat psoriasis, it may also make your psoriasis worse. This was not common in studies with calcipotriene, but it can happen.

To find out how often this side effect occurred in studies, see the prescribing information for calcipotriene. cream, ointment, and Solution.

It is not known why calcipotriene causes worsening of psoriasis in some people. But this side effect should go away if you stop your calcipotriene treatment.

If you think your psoriasis is getting worse after using topical calcipotriene, tell your doctor straight away. They will probably want to see you and examine your skin. If your doctor thinks that calcipotriene is the cause of your psoriasis worsening, they will probably ask you to stop using the medicine and switch to other treatment.

Allergic reaction

As with most medicines, some people may have an allergic reaction after using topical calcipotriene.

Symptoms of a mild allergic reaction can include:

A more serious allergic reaction is rare but possible. Symptoms of a severe allergic reaction can include:

  • swelling under the skin, usually on the eyelids, lips, hands or feet
  • swelling of the tongue, mouth, or throat
  • difficulty in breathing

Call your doctor right away if you have an allergic reaction to calcipotriene, as the reaction could get serious. Call 911 or your local emergency number if your symptoms are life-threatening or if you think you have a medical emergency.


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