May 11, 2022

Side effects, how it works, cost, alternatives, etc.

Libtayo can cause mild or severe side effects. The following lists contain some of the main side effects that can occur when taking Libtayo. The side effects of the medicine may differ slightly depending on whether Libtayo is used to treat skin cancer or lung cancer.

These lists do not include all possible side effects. For more information about the possible side effects of Libtayo, talk to your doctor or pharmacist. They can give you advice on how to deal with side effects that may be concerning or bothersome.

To note: The Food and Drug Administration (FDA) tracks the side effects of drugs it has approved. If you would like to notify the FDA about a side effect you have had with Libtayo, you can do so via MedWatch.

Mild side effects

Mild side effects* of Libtayo may include:

Most of these side effects may disappear within a few days or weeks. But if they get worse or don’t go away, talk to your doctor or pharmacist.

*This is a partial list of mild Libtayo side effects. For more information about other mild side effects, talk to your doctor or pharmacist, or see the Package Leaflet for Libtayo. prescribing information.
† For more information on this side effect, see “Details of side effects” below.

Serious side effects

Serious side effects may occur in some people during treatment with Libtayo. Call your doctor right away if you experience any serious side effects. Call 911 or your local emergency number if your symptoms are life-threatening or you think you have a medical emergency.

Serious side effects and their symptoms may include:

  • High blood pressure. Symptoms usually don’t occur, but very high blood pressure can cause:
  • Serious infections, such as pneumonia or cellulitis (bacterial skin infection). Symptoms vary but can include:
    • swollen, painful or sore areas of skin
    • cough that may produce yellow or green mucus
  • Blood disorders, such as lymphopenia (low lymphocyte count) and anemia (low red blood cell count). Symptoms can include:
    • increased risk of lymphopenia infection
    • fatigue, dizziness, or looking paler than usual with anemia
  • Other changes in blood test results, including changes in electrolyte levels, such as sodium, phosphate, and potassium. Symptoms can include:
  • Infusion-related reaction.*
  • Immune-mediated reaction*
  • Allergic reaction.*

* For more information on this side effect, see ‘Details of side effects’ below.

Details of side effects

Here are some details about some side effects that this drug can cause. To find out how often side effects occurred in clinical trials, see the prescribing information for Libtayo.

Infusion-related reaction

A healthcare professional will administer Libtayo by intravenous (IV) infusion. This is an injection into a vein given over a period of time. Libtayo infusions usually last about 30 minutes. It is possible to have side effects during the infusion. These reactions are called infusion-related reactions.

Symptoms of infusion-related reactions may include:

  • nausea
  • fever
  • itchy skin
  • wheezing or difficulty breathing
  • tremors or chills
  • rinsing
  • dizziness
  • feel like you might pass out

The healthcare professional will monitor you while you receive your infusion. Tell them immediately if you have symptoms. They can slow down or interrupt the infusion. If you experience a severe infusion-related reaction, such as difficulty in breathing, your doctor may ask you to stop treatment with Libtayo. In clinical testsserious infusion-related reactions were rare.

If you have any questions about Libtayo infusion reactions, talk to your doctor.

Tired

Fatigue is a possible side effect of Libtayo. It was one of the most common side effects observed in the treatment of the drug. clinical tests.

With fatigue, you may feel weak and tired even though you are sleeping normally.

If this side effect does not go away or gets worse, talk to your doctor. They may suggest ways to boost your energy levels, such as a daily walk or strength training (depending on your ability).

muscle or bone pain

Libtayo may cause muscle or bone pain. This side effect has been seen frequently in people taking Libtayo clinical tests. Some people have also reported joint, neck, and back pain or stiffness.

The severity of muscle or bone pain can vary from mild to severe.

Talk to your doctor if you have severe pain or pain that does not go away. They can suggest ways to manage this side effect, such as trying physical therapy or pain medication. Over-the-counter pain relievers may include acetaminophen (Tylenol). Prescription pain relievers can include opioids, such as hydromorphone (Dilaudide).

Immune-mediated reaction

Libtayo treats certain types of cancer by working with your immune system. In some cases, the drug can cause your immune system to mistakenly attack your healthy tissues and organs. This can lead to inflammation and damage in the affected tissues or organs. Doctors call this an “immune-mediated” reaction.

Immune-mediated reactions were uncommon in clinical tests. When they did occur, the rare cases were serious and sometimes fatal. In some people, immune-mediated reactions have been reported after stopping treatment with Libtayo.

Symptoms of immune-mediated reactions differ from typical symptoms of allergic reactions, such as skin rashes. And they vary depending on the tissues and organs affected.

Here are some examples of immune-mediated reactions that may occur with Libtayo:

  • Pneumonitis (inflammation of the lungs). Symptoms can include:
  • Hepatitis (inflammation of the liver). Signs and symptoms may include:
    • pain on the right side of your abdomen
  • Colitis (inflammation of the small intestine). Symptoms can include:
    • looser or more frequent stools than usual
  • Nephritis (inflammation of the kidneys). Symptoms can include:
    • produce less urine than usual
    • swelling of the lower legs or ankles
  • Thyroid problems. Symptoms can include:
    • weight gain or weight loss

Call your doctor right away if you have any of these symptoms with Libtayo. The sooner you receive treatment for these reactions, the less serious they are likely to become. Depending on the severity, your doctor may interrupt or stop your treatment with Libtayo. They may also recommend medication to help stop the reaction. For example, a corticosteroid such as prednisone (Rayos).

Allergic reaction

As with most medicines, some people may have an allergic reaction after receiving Libtayo.

Symptoms of a mild allergic reaction may include:

A more serious allergic reaction is rare but possible. Symptoms of a severe allergic reaction may include:

  • peeling skin or blisters
  • swelling under the skin, usually in the eyelids, lips, hands, or feet
  • swelling of the tongue, mouth or throat
  • difficulty breathing

Call your doctor right away if you have an allergic reaction to Libtayo, as the reaction could become serious. Call 911 or your local emergency number if your symptoms are life-threatening or you think you have a medical emergency.


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