The Food and Drug Administration (FDA) approves prescription drugs such as Inderal LA and Inderal XL to treat certain conditions. Inderal LA and Inderal XL can also be used off-label for other conditions. Off-label drug use occurs when an FDA-approved drug is prescribed for purposes other than those for which it is approved.
Inderal LA for migraine prevention
Inderal LA is FDA approved to help prevent migraine headaches in adults. Inderal XL is not approved for this use.
Inderal LA should not be taken to treat an episode of migraine that is already occurring. It is not known if the drug is safe or effective when used for this purpose. Your doctor will likely recommend a different medication to treat your migraine.
Migraine is a condition that can cause a headache with pain or throbbing. Migraine episodes can include other symptoms such as nausea, vomiting, or changes in vision. An episode can last from hours to days.
To learn more about migraine, check out our hub on headaches and migraine.
Effectiveness for the prevention of migraines
Inderal LA is an effective option to help prevent migraines. In fact, propranolol (the active medicinal ingredient in Inderal LA) is recommended in guidelines for migraine prevention. The guidelines come from the American Academy of Neurology and the American Headache Society.
For more details on the performance of Inderal LA in clinical trials, see its prescribing information.
Inderal LA for stable angina
Inderal LA is FDA-approved for use in adults with a condition known as stable angina. The drug is used to decrease how often stable angina occurs. The drug is also used to help improve the ability to exercise. This could mean that you are able to do more activities without experiencing stable angina symptoms.
Inderal XL is not approved to treat stable angina.
Stable angina explained
Stable angina (also called angina pectoris) is a condition that can cause chest pain. Stable angina occurs during activities, such as exercise, or when you feel stressed. It usually goes away when you rest. This condition is caused by decreased blood flow to your heart, causing your heart to receive less oxygen than it needs. Symptoms may include:
To learn more about stable angina, visit our Cardiovascular Health Center.
Efficacy for stable angina
Inderal LA is an effective treatment option for treating stable angina. Beta-blockers such as Inderal LA are recommended medications for adults with stable angina undergoing treatment
For more details on the performance of Inderal LA in clinical trials, see the drug fact sheet. prescribing information.
Inderal LA for hypertrophic subaortic stenosis
Inderal LA is FDA-approved to treat symptoms of a heart condition called hypertrophic subaortic stenosis (HSS) in adults. The drug is used to help reduce the severity of SHS.
To measure the severity of SHS, doctors use a
Inderal XL is not currently approved to treat HSS.
Explanation of hypertrophic subaortic stenosis
HSS is a condition that occurs when the heart muscle becomes too thick. This makes it harder than usual for blood to flow through your heart. Symptoms of this condition may include:
To learn more about RSS, check out our Heart Health Center.
Efficacy for hypertrophic subaortic stenosis
Inderal LA is an effective treatment option for adults with SHS. In fact, beta-blockers such as Inderal LA are recommended options in the treatment
For more details on how Inderal LA performed in clinical trials, see the drug fact sheet. prescribing information.
Inderal LA and Inderal XL for high blood pressure
Inderal LA and Inderal XL are FDA approved to help manage high blood pressure.
In some cases, your doctor may recommend that you take another medicine, called a thiazide diuretic, in combination with Inderal LA. This can help manage your blood pressure better.
It is important to note that Inderal LA is not approved to treat a hypertensive emergency (dangerously high blood pressure).
High blood pressure explained
High blood pressure is a very common condition. Your blood pressure is determined by the force of your blood pushing against the walls of your arteries. If your blood pressure is too high, it can increase your risk of developing other problems such as:
High blood pressure usually causes no symptoms. When it gets very high, possible symptoms can include headaches, nosebleeds, chest pain, and difficulty breathing.
To learn more about high blood pressure, visit our Heart Health Center.
Effectiveness for high blood pressure
Inderal LA and Inderal XL are effective treatment options for adults with high blood pressure. Although these medications are not the first treatment options for high blood pressure, they are recommended in treatment guidelines.
Specifically, beta-blockers such as Inderal LA or Inderal XL are recommended as options for high blood pressure in treatment guidelines. Guidelines come from the ACC and AHA.
Inderal LA and Inderal XL and children
Neither Inderal LA nor Inderal XL is approved to be prescribed for children. It is not known if these drugs are safe or effective for this age group.
However, there is another form of propranolol (the active ingredient in Inderal LA and Inderal XL) that is approved for use in children. The drug is called Hemangeol and is used to treat blood vessel conditions called hemangiomas.
You can discuss treatment options for your child’s condition with your child’s doctor.