May 11, 2022

Uses, Dosage, Side Effects & More

Like most medicines, Tazorac can cause mild or severe side effects. The lists below describe some of the more common side effects that Tazorac can cause. These lists do not include all possible side effects.

Keep in mind that the side effects of a medicine can depend on:

  • your age
  • other health problems you have
  • other medicines you are taking

Your doctor or pharmacist can tell you more about the potential side effects of Tazorac. They can also suggest ways to help reduce side effects.

Mild side effects

Here is a short list of some of the mild side effects that Tazorac can cause. To learn about other mild side effects, talk to your doctor or pharmacist, or read the prescribing information for Tazorac cream Where gel. Side effects may differ slightly depending on whether you are using the drug to treat acne or plaque psoriasis.

Mild side effects of Tazorac that have been reported include:

  • burning sensation*
  • scaly or peeling skin
  • itchy, irritated and swollen areas of skin
  • redness or discoloration of the skin
  • dry skin*

* For more information on this side effect, see the “Side Effect Focus” section below.

Mild side effects of many medications can disappear within days to weeks. But if they become bothersome, talk to your doctor or pharmacist.

Serious side effects

Serious side effects from Tazorac can occur, but they are not common. If you have serious side effects from Tazorac, call your doctor right away. But if you think you have a medical emergency, call 911 or your local emergency number.

Serious side effects of Tazorac that have been reported include:

* For more information on this side effect, see the “Side Effect Focus” section below.

Focus on side effects

Learn more about some of the side effects Tazorac can cause.

Burning sensation

It is common to feel a tingling or burning sensation when using Tazorac cream or gel. In studies, this was a common side effect in people who used Tazorac cream Where gel for acne or plaque psoriasis.

Your skin may feel itchy or burning right after applying Tazorac. Or these sensations can come and go at any time while you are using the treatment. This irritation may be more noticeable if you are outdoors in cold or windy weather.

For most people, this side effect is mild and temporary.

What might help

To help prevent or minimize this side effect, it is important to follow Tazorac’s instructions for use carefully. Here are some tips to keep in mind:

  • Be sure to apply only a thin layer of gel or cream.
  • Avoid areas of your skin affected by eczema.
  • Apply Tazorac only to areas affected by your skin condition (acne or plaque psoriasis).

Also consult your doctor before using any other skin care products or topical medications while using Tazorac. They will let you know if you should avoid any ingredients that may irritate your skin.

If you have a burning sensation that doesn’t go away or gets worse, talk to your doctor. Your doctor can determine if you should continue your treatment with Tazorac.

Dry skin

Dry skin is a common side effect of Tazorac. In studies, this side effect occurred commonly in people who used Tazorac cream Where gel to treat acne or plaque psoriasis.

Dry skin can be itchy and uncomfortable, and it can lead to further irritation if you scratch it. Scratching can also trigger a flare-up in people with plaque psoriasis.

What might help

Consult your doctor before using other skin care products or topical medications while using Tazorac. They will let you know if you should avoid ingredients that could dry out your skin.

Drinking plenty of water and using a humidifier in your home can also help relieve dry skin.

If these tips don’t help, or if your dry skin seems severe, talk to your doctor. They may suggest other ways to relieve this side effect.

Allergic reaction

Some people may have an allergic reaction to Tazorac.

Symptoms of a mild allergic reaction may include:

  • itchy skin
  • itching
  • rinsing (temporary warmth, redness or deepening of skin color)

A more serious allergic reaction is rare but possible. Symptoms of a severe allergic reaction can include swelling under the skin, usually on the eyelids, lips, hands or feet. They can also include swelling of the tongue, mouth, or throat, which can lead to difficulty breathing.

Call your doctor right away if you have an allergic reaction to Tazorac. But if you think you have a medical emergency, call 911 or your local emergency number.


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