It is very important that your doctor checks your progress at regular visits to make sure this medicine is working properly. Blood and urine tests may be needed to check for side effects.
Using this medication while you are pregnant may harm your unborn baby, especially in your second or third trimester. Use an effective form of birth control to avoid getting pregnant. If you think you may have become pregnant while using this medication, tell your doctor immediately. You may need to stop using this medicine.
You should not use this medicine with sacubitril. Do not use this medication and sacubitril/valsartan (Entresto®) within 36 hours of each other.
This medicine can cause a serious type of allergic reaction, including anaphylaxis, which can be life threatening and requires immediate medical attention. Call your doctor right away if you have a rash, itching, hoarseness, difficulty breathing, difficulty swallowing, or any swelling of your hands, face, or mouth while using this medication.
Call your doctor right away if you have severe abdominal pain (with or without nausea or vomiting). This could be a symptom of a condition called intestinal angioedema.
Dizziness, lightheadedness, or fainting may also occur, especially when you get up suddenly from a lying or sitting position or if you have taken a diuretic (water pill). . If you feel dizzy, lie down so you don’t pass out. Then sit down for a few moments before getting up to prevent dizziness from returning.
Consult your doctor immediately if you become ill while taking this medication, especially if you experience severe or continuous nausea, vomiting, or diarrhea. These conditions can cause you to lose too much water or salt and can lead to low blood pressure. You can also lose water through sweating, so drink plenty of water during exercise or in hot weather.
This medication may affect blood sugar. If you notice a change in your blood sugar or urine test results, or have any questions, see your doctor.
See your doctor if you have a fever, chills, or sore throat. These could be symptoms of an infection resulting from a low white blood cell count.
See your doctor right away if you experience upper stomach pain or tenderness, pale stools, dark urine, loss of appetite, nausea, or yellow eyes or skin. These could be symptoms of a serious liver problem.
Consult your doctor immediately if blurred vision, difficulty reading, eye pain, or any other change in vision occurs during or after treatment. It could be a sign of a serious eye problem. Your doctor may ask an ophthalmologist (ophthalmologist) to check your eyes.
See your doctor right away if you have bloody urine, decreased frequency or amount of urination, increased blood pressure, increased thirst, loss of appetite, lower or side pain, nausea, swelling of the face, fingers or lower legs, difficulty breathing, unusual tiredness or weakness, vomiting or weight gain. These could be symptoms of a serious kidney problem.
Hyperkalemia (high blood potassium) may occur while you are using this medication. See your doctor right away if you have stomach pain, confusion, irregular heartbeat, nausea or vomiting, nervousness, numbness or tingling in your hands, feet or lips, difficulty breathing or weakness or heaviness in the legs. Ask your doctor before using any medicine, supplement, or salt substitute that contains potassium.
This medicine may increase your risk of developing skin cancer (eg, non-melanoma skin cancer). Avoid sun exposure. Use sunscreen when outdoors. Avoid sunlamps and tanning beds. Talk to your doctor if you have any concerns about this risk.
Make sure any doctor or dentist who treats you knows you are using this medicine. You may need to stop using this medicine several days before having surgery.
This drug may be less effective in black patients. Black patients also have an increased risk of swelling of the hands, arms, face, mouth or throat. Talk to your doctor if you have any concerns about this.
Alcohol, narcotic pain medications, or sleeping pills may cause dizziness, lightheadedness, or fainting when used with this medication. Tell your doctor if you drink alcohol or use painkillers or sleeping pills.
Do not take any other medicines unless they have been discussed with your doctor. This includes prescription or over-the-counter (OTC) medications [OTC]) medications for appetite control, asthma, colds, coughs, hay fever, or sinus problems, and herbal or vitamin supplements.